Basic Science and Genetic Research Studies

In this project, we use an approach to “pathway” definition using gene expression data that can unite a number of autism-implicated common polymorphisms and rare variants into a network with functional implications.

This study will investigate maternal genetic factors for the Early Markers for Autism study, an ongoing epidemiologic investigation of immunologic and environmental markers for ASDs in maternal prenatal and newborn blood samples.

The purpose of these studies is to identify genetic, molecular and cellular mechanisms that control how the forebrain develops in normal and mutant mice. We are particularly interested in studying genes that contribute to autism susceptibility.